The bestselling author of Intern and Doctored tells the story of the thing that makes us tick For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As the cardiologist and bestselling author Sandeep Jauhar shows in Heart: A History, it was only recently that we demolished age-old taboos and devised the transformative procedures that have changed the way we live. Deftly alternating between key historical episodes and his own work, Jauhar tells the colorful and little-known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ. He introduces us to Daniel Hale Williams, the African American doctor who performed the world's first open heart surgery in Gilded Age Chicago. We meet C. Walton Lillehei, who connected a patient's circulatory system to a healthy donor's, paving the way for the heart-lung machine. And we encounter Wilson Greatbatch, who saved millions by inventing the pacemaker--by accident. Jauhar deftly braids these tales of discovery, hubris, and sorrow with moving accounts of his family's history of heart ailments and the patients he's treated over many years. He also confronts the limits of medical technology, arguing that future progress will depend more on how we choose to live than on the devices we invent. Affecting, engaging, and beautifully written, Heart: A History takes the full measure of the only organ that can move itself.

A young, hopeful doctor's memoir--an unforgettable love story and an informative journey into the world of medicine and kidney transplantation that ultimately asks: What does it mean to let go of something that you love, even if it is life itself? When Vanessa fell in love with Robert, she had no idea that the relationship would thoroughly transform her life. Robert suffered from end-stage kidney disease, which required him to endure years of debilitating dialysis to stay alive, at least until his failed organ could be replaced by a kidney transplant. Although Vanessa was a primary care doctor, she developed a deeper understanding of the difficulties Robert faced with dialysis and in finding a donor. Despite their being early in their relationship, she volunteered one of her own kidneys--and discovered that she was a match. This life-affirming experience forged a bond that would become a pillar of Vanessa and Robert's marriage--and the beginning of her new career. Motivated by Robert's experience and her newfound knowledge, Vanessa became a nephrologist--a kidney doctor--and discovered far more about the realities of the specialty. Shaped by Vanessa's remarkable experiences as a doctor, a woman of color, a mother, and a kidney donor, Hundreds of Interlaced Fingers is a love story, an exposé, and a clarion call for us all to consider the dualities of both loving and letting go.

The 1980s marked a revolution in the field of organ transplants, and Bud Shaw, M.D., was on the front lines. Now retired from active practice, Dr. Shaw relays gripping moments of anguish and elation, frustration and reward, despair and hope in his struggle to save patients. Within each emotionally charged vignette lie quieter moments, too, like growing up in rural Ohio, and being awakened late at night by footsteps in the hall as his father, also a surgeon, slipped out of the house to attend to a patient in the ER. Exhilarating, fast-paced and beautifully written.

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A fascinating exploration of the skin in its multifaceted physical, psychological, and social aspects Providing a cover for our delicate and intricate bodies, the skin is our largest and fastest-growing organ. We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

For a generation of American League baseball fans, Rod Carew was the definition of "batting champion." An insecure boy from Panama raised by a brutal father, Carew ascended to baseball stardom, tormenting pitchers with a smooth swing from a crouched stance and winning seven batting titles on his way to the Hall of Fame. It wasn't until he lost his beautiful 17-year-old daughter to an aggressive and rare form of leukemia that Carew had to re-gather himself and find new purpose outside of baseball. Then he was struck with a near-fatal heart attack and discovered that the heart transplant he received came from a 29-year-old pro football player whom he happened to have met years before. Now the parents of Konrad Reuland listen to their son's heart beating strong in Carew's chest, and Carew works to honor his daughter's wish that he "make a difference." Carew uses his own journey to show readers that regardless of what you may be facing-heart disease, cancer, divorce, an abusive relationship, premature retirement-you can persist and grow with the kind of grace, character, and determination that he learned to cultivate on the field and beyond.

It wasn't supposed to be this hard. If America could send a man to the moon, shouldn't the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature's greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting fifty years of false starts, abysmal failures and miraculous triumphs, as experienced by one the world's foremost heart surgeons, O.H. "Bud" Frazier, who has given his life to saving the un-savable.   His journey takes him from a small town in west Texas to one of the country's most prestigious medical institutions, The Texas Heart Institute, from the halls of Congress to the animal laboratories where calves are fitted with new heart designs. The roadblocks to success --medical setbacks, technological shortcomings, government regulations - are immense. Still, Bud and his associates persist, finding inspiration in the unlikeliest of places. A field beside the Nile irrigated by an Archimedes screw. A hardware store in Brisbane, Australia. A seedy bar on the wrong side of Houston. Until post WWII, heart surgery did not exist. Ticker provides a riveting history of the pioneers who gave their all to the courageous process of cutting into the only organ humans cannot live without. Heart surgeons Michael DeBakey and Denton Cooley, whose feud dominated the dramatic beginnings of heart surgery. Christian Barnaard, who changed the world overnight by performing the first heart transplant. Inventor Robert Jarvik, whose artificial heart made patient Barney Clark a worldwide symbol of both the brilliant promise of technology and the devastating evils of experimentation run amuck. Rich in supporting players, Ticker introduces us to Bud's brilliant colleagues in his quixotic quest to develop an artificial heart: Billy Cohn, the heart surgeon and inventor who devotes his spare time to the pursuit of magic and music; Daniel Timms, the Brisbane biomedical engineer whose design of a lightweight, pulseless heart with but a single moving part offers a new way forward.  And, as government money dries up, the unlikeliest of backers, Houston's furniture king, Mattress Mack.   In a sweeping narrative of one man's obsession, Swartz raises some of the hardest questions of the human condition. What are the tradeoffs of medical progress?   What is the cost, in suffering and resources, of offering patients a few more months, or years of life? Must science do harm to do good?  Ticker takes us on an unforgettable journey into the power and mystery of the human heart.

"With When Death Becomes Life, Joshua Mezrich has performed the perfect core biopsy of transplantation--a clear and compelling account of the grueling daily work, the spell-binding history and the unsettling ethical issues that haunt this miraculous lifesaving treatment. Mezrich's compassionate and honest voice, punctuated by a sharp and intelligent wit, render the enormous subject not just palatable but downright engrossing."--Pauline Chen, author of Final Exam: A Surgeon's Reflections on Mortality A gifted surgeon illuminates one of the most profound, awe-inspiring, and deeply affecting achievements of modern day medicine--the movement of organs between bodies--in this exceptional work of death and life that takes its place besides Atul Gawande's Complications, Siddhartha Mukherjee's The Emperor of All Maladies, and Jerome Groopman's How Doctors Think. At the University of Wisconsin, Dr. Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day. When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality--maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world. Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too. When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich's riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

Engaging, funny, and unflinching essays about coming of age as a transplant patient and living each day as a gift Adina Talve-Goodman was born with a congenital heart condition and survived multiple operations over the course of her childhood, including a heart transplant at age nineteen. In these seven essays, she tells the story of her chronic illness and her youthful search for love and meaning, never forgetting that her adult life is tied to the loss of another person--the donor of her transplanted heart. Whether writing about the experience of taking her old heart home from the hospital (and passing it around the Thanksgiving table), a summer camp for young transplant patients, or a memorable night on the town, Talve-Goodman's writing is filled with curiosity, humor, and compassion. Published posthumously, Your Hearts, Your Scars is the work of a writer wise beyond her years, a moving reflection on chance and gratitude, and a testament to hope and kindness.

In this emotionally candid contemporary YA, author Jen Malone delves into the world of a teen whose life is brought to an abrupt halt when she learns she's in dire need of an organ transplant. Hard-charging and irrepressible, eighteen-year-old Amelia Linehan could see a roller derby opponent a mile away--and that's while crouched down, bent over skates, and zooming around a track at the speed of light. What she couldn't see coming, however, was the flare-up of the rare liver disorder she was born with. But now it's the only thing she--and everyone around her--can think about.   With no guarantee of a viable organ transplant, everything Amelia's been sure of--like college plans or the possibility of one day falling in love--has become a huge question mark, threatening to drag her down into a sea of what-ifs she's desperate to avoid. Then a friend from the past shows up. With Will, it's easy to forget about what's lurking between the lightness of their time together. She feels alive when all signs point elsewhere. But with the odds decidedly not in her favor, Amelia knows this feeling can't last forever. After all, what can?

For centuries, people misunderstood how the heart works. As our knowledge grew, heart surgery remained a dangerous medical procedure. Even after organ transplants become common, surgeons struggled to transplant hearts and keep patients alive. But small groups of pioneering doctors attempted this difficult surgery, changing the lives of patients. This graphic history traces their leap forward and the medical world's newest advancements in heart-health technology. Learn about innovations such as artificial hearts and 3D printed living tissue.

Bestselling author ofAll the Bright Places Jennifer Niven calls emerging talent Shivaun Plozza's charming and romantic second YA novel,Tin Heart, "from cover to cover swoon-worthy, moving, deep, and funny"! When Marlowe gets a heart transplant and a second chance at life, all she wants to do is to thank her donor's family. Maybe then she can move on. Maybe then she'll discover who she is if she's no longer The Dying Girl. But with a little brother who dresses like every day is Halloween, a vegan warrior for a mother, and an all-out war with the hot butcher's apprentice next door, Marlowe's life is already pretty complicated. And her second chance is about to take an unexpected turn...

With trusted expertise from Mayo Clinic, the Edge of Medicine series sets out to inspire and educate the next generation of young scientists by highlighting the medical breakthroughs of a diverse range of scientists and researchers. From the first immunosuppressant drugs to the first successful heart transplant, this exploration of scientific inquiry celebrates the greatest developments to date in transplant medicine. Get to know the physicians, scientists, and other researchers responsible for these breakthroughs in medicine, and explore the ups, the downs, and the eureka moments that are science in action. Mayo Clinic Press Kids creates empowering health and wellness content in partnership with pediatric experts. Proceeds from the sale of every book go to benefit important medical research and education at Mayo Clinic.

One of PopSugar's Best New YA Novels of 2021 A Buzzfeed Top LGBTQ+ YA Book A Lambda Literary YA Book to Add to Your TBR Pile A Goodreads Pride Month Pick An epic, heartfelt romance about a boy torn between two loves, one in his present ... and one in the past. A story of Black queer history, love, loss, and learning to stay in the moment before it passes you by. Weeks ago, Andre Cobb received a much-needed liver transplant. He's ready for his life to finally begin, until one night, when he passes out and wakes up somewhere totally unexpected...in 1969, where he connects with a magnetic boy named Michael. And then, just as suddenly as he arrived, he slips back to present-day Boston, where the family of his donor is waiting to explain that his new liver came with a side effect-the ability to time travel. And they've tasked their youngest son, Blake, with teaching Andre how to use his unexpected new gift. Andre splits his time bouncing between the past and future. Between Michael and Blake. Michael is everything Andre wishes he could be, and Blake, still reeling from the death of his brother, Andre's donor, keeps him at arm's length despite their obvious attraction to each other. Torn between two boys, one in the past and one in the present, Andre has to figure out where he belongs-and more importantly who he wants to be-before the consequences of jumping in time catch up to him and change his future for good.

For fans of Josie Silver's One Day in December, The Curious Heart of Ailsa Rae is a wholly original, charismatic, and uplifting novel that no reader will soon forget. Ailsa Rae is learning how to live. She's only a few months past the heart transplant that--just in time--saved her life. Now, finally, she can be a normal twenty-eight-year-old. She can climb a mountain. Dance. Wait in line all day for tickets to Wimbledon. But first, she has to put one foot in front of the other. So far, things are as bloody complicated as ever. Her relationship with her mother is at a breaking point and she wants to find her father. Then there's Lennox, whom Ailsa loved and lost. Will she ever find love again? Her new heart is a bold heart. She just needs to learn to listen to it. From the hospital to her childhood home, on social media and IRL, Ailsa will embark on a journey about what it means to be, and feel, alive. How do we learn to be brave, to accept defeat, to dare to dream? From Stephanie Butland, author of The Lost for Words Bookshop, The Curious Heart of Ailsa Rae will warm you from the inside out.

Just before dawn on a Sunday morning, three teenage boys go surfing. Returning home, exhausted, the driver lets the car drift off the road into a tree. Two of the boys are wearing seat belts; one is sent through the windshield. He is declared brain-dead shortly after arriving at the hospital. His heart is still beating. The Heart takes place over the twenty-four hours surrounding a fatal accident and a resulting heart transplant as life is taken from a young man and given to a woman close to death. In gorgeous, ruminative prose it examines the deepest feelings of everyone involved--grieving parents, hardworking doctors and nurses--as they navigate decisions of life and death. As stylistically audacious as it is emotionally explosive, Maylis de Kerangal's The Heart has mesmerized readers in France, where it has been hailed as the breakthrough work of a new literary star.

A novel of terrible first impressions, hilarious second chances, and the joy in finding your perfect match from "a true talent" (Emily Henry, #1 New York Times bestselling author). Dr. Briana Ortiz's life is seriously flatlining. Her divorce is just about finalized, her brother's running out of time to find a kidney donor, and that promotion she wants? Oh, that's probably going to the new man-doctor who's already registering eighty-friggin'-seven on Briana's "pain in my ass" scale. But just when all systems are set to hate, Dr. Jacob Maddox completely flips the game . . . by sending Briana a letter. And it's a really good letter. Like the kind that proves that Jacob isn't actually Satan. Worse, he might be this fantastically funny and subversively likeable guy who's terrible at first impressions. Because suddenly he and Bri are exchanging letters, sharing lunch dates in her "sob closet," and discussing the merits of freakishly tiny horses. But when Jacob decides to give Briana the best gift imaginable--a kidney for her brother--she wonders just how she can resist this quietly sexy new doctor . . . especially when he calls in a favor she can't refuse. "Abby Jimenez's words...sprinkle humor and warmth all over my life." -Ali Hazelwood, New York Times bestselling author of The Love Hypothesis